Recent Publications

A compilation of recent publications in the field of complement research and from members of Complement UK

Paper reference
Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration
Paper authors
Thomas M. Hallam; Kevin J. Marchbank; Claire L. Harris; Clive Osmond; Victoria G. Shuttleworth; Helen Griffiths; Angela J. Cree; David Kavanagh; Andrew J. Lotery
32516404
Paper reference
The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy
Paper authors
Nilufar Kadkhodayi-Kholghi1, Jayesh S. Bhatt1, Jayesh Gor2, Lindsay C. McDermott3, Daniel P Gale4 and Stephen J. Perkins5*
Paper reference
Rationale for targeting complement in COVID-19
Paper authors
Anastasia Polycarpou 1 , Mark Howard 1 , Conrad A Farrar 1 , Roseanna Greenlaw 1 , Giorgia Fanelli 1 , Russell Wallis 2 , Linda S Klavinskis 3 , Steven Sacks 1
32559343
Paper reference
Fucose as a new therapeutic target in renal transplantation
Paper authors
Mark C Howard 1 , Christopher L Nauser 2 , Daniela A Vizitiu 3 , Steven H Sacks 2
32472330
Paper reference
Complement-Independent Modulation of Influenza A Virus Infection by Factor H.
Paper authors
Murugaiah V, Varghese PM, Saleh SM, Tsolaki AG, Alrokayan SH, Khan HA, Collison KS, Sim RB, Nal B, Al-Mohanna FA, Kishore U.
32269562
Paper reference
l‐Fucose prevention of renal ischaemia/reperfusion injury in Mice
Paper authors
Mark C. Howard Christopher L. Nauser Conrad A. Farrar Russell Wallis Steven H. Sacks
Paper reference
Prognostic Implications of the Complement Protein C1q in Gliomas.
Paper authors
Alessandro Mangogna 1 , Beatrice Belmonte 2 , Chiara Agostinis 3 , Paola Zacchi 1 , Domenico Gerardo Iacopino 4 , Anna Martorana 5 , Vito Rodolico 5 , Deborah Bonazza 6 , Fabrizio Zanconati 6 , Uday Kishore 7 , Roberta Bulla 1
31649675
Paper reference
Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients.
Paper authors
DeCordova S1, Abdelgany A2, Murugaiah V1, Pathan AA1, Nayak A1, Walker T3, Shastri A4, Alrokayan SH5, Khan HA5, Singh SK6, De Pennington N3, Sim RB7, Kishore U8.
31519376
Paper reference
The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury
Paper authors
Qi Peng1,4, Weiju Wu1,4, Kun-Yi Wu2, Bo Cao2, Cui Qiang1,3, Ke Li2, Steven H. Sacks1, Wuding Zhou1

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