Recent Publications

A compilation of recent publications in the field of complement research and from members of Complement UK

Paper reference
Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients.
Paper authors
DeCordova S1, Abdelgany A2, Murugaiah V1, Pathan AA1, Nayak A1, Walker T3, Shastri A4, Alrokayan SH5, Khan HA5, Singh SK6, De Pennington N3, Sim RB7, Kishore U8.
31519376
Paper reference
The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury
Paper authors
Qi Peng1,4, Weiju Wu1,4, Kun-Yi Wu2, Bo Cao2, Cui Qiang1,3, Ke Li2, Steven H. Sacks1, Wuding Zhou1
Paper reference
The C3a/C3aR axis mediates anti-inflammatory activity and protects against uropathogenic E coli-induced kidney injury in mice.
Paper authors
Wu KY1, Zhang T1, Zhao GX1, Ma N1, Zhao SJ1, Wang N1, Wang JX1, Li ZF2, Zhou W3, Li K4.
Paper reference
Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease.
Paper authors
Carter SA1, Lightstone L2, Cattran D3, Bagga A4, Barbour SJ5, Barratt J6, Boletis J7, Caster D8, Coppo R9, Fervenza FC10, Floege J11, Hladunewich M12, Hogan JJ13, Kitching AR14, Lafayette R15, Malvar A16, Radhakrishnan J17, Rovin BH18, Zhang H19, Gutman T20, Howell M20, Logeman C21, Shen JI22, Teixeira-Pinto A20, Alexander SI21, Cho Y23, Craig JC24, Harris D25, Johnson DW23, Kerr PG14, Ryan J26, Viecelli AK27, Wang AY28, Wilkie M29, Scholes-Robertson N21, Tong A20; SONG-GD Initiative.
31122702
Paper reference
Loss-of-function mutations in the CFH gene affecting alternatively encoded Factor H-like 1proteincause dominant early-onset macular drusen.
Paper authors
Smith-Jackson K1,2,Yang Y1,Denton H1,Pappworth IY1,Cooke K1,Barlow PN3,Atkinson JP4,Liszewski MK4,Pickering MC5,Kavanagh D1,2,Cook HT5,Marchbank KJ1,2
30714990
Paper reference
Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System.
Paper authors
Carpanini SM1, Torvell M1, Morgan BP1,2.
30886620
Paper reference
Diagnostic Indicators of Superimposed Preeclampsia in Women With CKD.
Paper authors
Wiles K1, Bramham K2, Seed PT3, Kurlak LO4, Mistry HD4, Nelson-Piercy C5, Lightstone L6, Chappell LC3.
31194119
Paper reference
Glomerular membrane attack complex is not a reliable marker of ongoing C5 activation in lupus nephritis.
Paper authors
Wilson HR1, Medjeral-Thomas NR1, Gilmore AC1, Trivedi P1, Seyb K2, Farzaneh-Far R2, Gunnarsson I3, Zickert A3, Cairns TD1, Lightstone L1, Cook HT4, Pickering MC1.
30655025
Paper reference
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.
Paper authors
Smith-Jackson K1,2,Yang Y1,Denton H1,Pappworth IY1,Cooke K1,Barlow PN3,Atkinson JP4,Liszewski MK4,Pickering MC5,Kavanagh D1,2,Cook HT5,Marchbank KJ1,2
30714990

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