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The 7th “Complement UK Training Course and Symposium” will take place on April, 3rd and 4th 2023, hosted by Cardiff University. This year’s event will focus on Complement Diagnostics and Therapeutics.

These meetings are for scientists, clinicians, and pre- and post-doctoral researchers, industrial partners interested in complement biology. We particularly welcome the active participation of early career researchers and have included several slots in our programme for short talks, based on abstract submissions. There will be prizes for best poster and oral presentation.


The first day is a teaching day focused on trainees, students and junior Post Docs. There will be introductory lectures on complement, followed by a choice of tutorials covering many aspects of basic complement biology and biochemistry, and the role of complement in disease. Following the tutorials there will be a guest talk by Professor Sir Leszek Borysiewicz.

There is a choice of two tutorials in the morning and two in the afternoon, which are intended to give tutees a grounding in essential basic points which will underpin the rest of the meeting.

*(only for students and newcomers to complement)


The symposium on the second day will expand on a specific research theme, which this year is the role of complement in diagnostics and therapeutics. The meeting will end with a roundtable discussion.

Guest Speaker

Professor Sir Leszek Borysiewicz

"Cancer and Inflammation"

Scientific Organisers

Dr Wioleta Zelek
Cardiff University

Professor Paul Morgan
Cardiff University

Meeting Manager

Anna Taliadoros


Register now: 

Meet the Speakers and Tutors


Monday, April 3rd:   TRAINING DAY

09:30 – 11:00           COMPLEMENT TUTORIAL 1

1.1 Compartmentalisation of complement – Steven Sacks

1.2 Complement and break of tolerance – Marina Botto

2.1 Complement association with disease – Simon Clark

2.2 Complement association with disease – Meike Heurich-Sevcenco

11:30 – 12:15    Lecture: Complement; the basics – Paul Morgan

12:15 – 12:45    Quick-fire poster presentations (one slide, 60 seconds)

13:45 – 15:15           COMPLEMENT TUTORIAL 2

3.1 Complement & therapeutics – Matthew Pickering

3.2 Complement & therapeutics – Claire Harris

4.1 Diagnostics; genetics – David Kavanagh

4.2 Diagnostics; biomarkers/assays –Loek Willems and Erik Toonen

15:45 – 17:05                   ABSTRACT PRESENTATIONS

1550 – 1605       Lack of Complement Factor H contributes to endothelial cell injury in Shiga toxin Haemolytic Uraemic Syndrome, Emily Bowen

1605 – 1620       Safety, Tolerability and Pharmacodynamic Effects of ARO-C3, a Subcutaneously Administered Investigational RNAi Therapeutic Targeting Complement C3, in Adult Healthy Volunteers, Hamid Moradi

1620 – 1635       GWAS of plasma complement protein levels reveals functional effects of Alzheimer’s disease risk loci, Aurora Veteleanu

1635 – 1650       Complement receptor 1 is expressed on brain cells and impacts roles of microglia relevant to Alzheimer’s disease, Nikoleta Daskoulidou

1650 – 1705       Complement inhibitors for age-related macular degeneration (AMD): A Cochrane systematic review and meta-analysis, Nikolaos Tzoumas

17:05 – 18:05   Guest lecture "Cancer and Inflammation", Professor Sir Leszek Borysiewicz

18:15 – Poster presentations and Drinks Reception

19:30 – Conference Dinner

Sponsor of Conference Dinner

Tuesday, April 4th:   SYMPOSIUM

08:45 – 12:15           SESSION 1: THERAPIES

08:45 – 09:15   Therapeutic targets – overview - Claire Harris

09:15 – 09:45   Anti-complement drugs in disease; Lessons from animal models – Kevin Marchbank

09:45 – 10:15   C5 vs. C3 based therapeutic approaches in kidney disease (including eculizumab withdrawal trials - Neil Sheerin

10:15 – 10:45   C5 vs. C3 based approaches in PNH - Richard Kelly

11:15– 11:45    Targeting complement at the genetic level - Scott Ellis

11:45 – 12:15   Designing anti-complement drugs through structural studies - Jean Van Den Elsen & Alex Macpherson

13:30 – 15:30 SESSION 2: Mechanisms and Diagnostics

13:30 – 14:00   Complement and genetics - Santiago Rodriguez de Cordoba

14:00 – 14:30   Pitfalls in complement analyses – Erik Toonen

14:30 – 15:00   New technologies for studying complement in brain – Soyon Hong

15:00 – 15:30   Lectin Pathway - Wilhelm Schwaeble

15:30 – 15:45   Prizes for best posters / presentations / tutor

15:45 – 16:30   Round table discussion

Is there a single best target for anti-complement drugs?





Posters should be in A0 (841 mm x 1189 mm), in portrait orientation.


Sponsor of Prizes for best poster and oral presentations

Event Location

Cardiff University

Hadyn Ellis Building

Maindy Road,

CF24 4HQ Cardiff

Dinner on April 3rd

Cardiff University
Aberdare Hall
Corbett  Road,
CF10 3UP Cardiff

Become a Sponsor

A number of sponsor opportunities are available for companies looking to meet new customers and reinforce
existing relationships. 

Posters, refreshments, coffee, and all networking breaks will take place in the exhibit hall to ensure high-quality networking. 

Contact us for more details on our sponsorship opportunities