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The 7th “Complement UK Training Course and Symposium” will take place on April, 3rd and 4th 2023, hosted by Cardiff University. This year’s event will focus on Complement Diagnostics and Therapeutics.
These meetings are for scientists, clinicians, and pre- and post-doctoral researchers, industrial partners interested in complement biology. We particularly welcome the active participation of early career researchers and have included several slots in our programme for short talks, based on abstract submissions. There will be prizes for best poster and oral presentation.
TUTORIALS*
The first day is a teaching day focused on trainees, students and junior Post Docs. There will be introductory lectures on complement, followed by a choice of tutorials covering many aspects of basic complement biology and biochemistry, and the role of complement in disease. Following the tutorials there will be a guest talk by Professor Sir Leszek Borysiewicz.
There is a choice of two tutorials in the morning and two in the afternoon, which are intended to give tutees a grounding in essential basic points which will underpin the rest of the meeting.
*(only for students and newcomers to complement)
SYMPOSIUM
The symposium on the second day will expand on a specific research theme, which this year is the role of complement in diagnostics and therapeutics. The meeting will end with a roundtable discussion.
Guest Speaker
Professor Sir Leszek Borysiewicz
"Cancer and Inflammation"
Scientific Organisers
Dr Wioleta Zelek
Cardiff University
Professor Paul Morgan
Cardiff University
Meeting Manager
Anna Taliadoros
anna.taliadoros@kcl.ac.uk
Register now:
Meet the Speakers and Tutors
PROGRAMME HIGHLIGHTS
Monday, April 3rd: TRAINING DAY
09:30 – 11:00 COMPLEMENT TUTORIAL 1
1.1 Compartmentalisation of complement – Steven Sacks
1.2 Complement and break of tolerance – Marina Botto
2.1 Complement association with disease – Simon Clark
2.2 Complement association with disease – Meike Heurich-Sevcenco
11:30 – 12:15 Lecture: Complement; the basics – Paul Morgan
12:15 – 12:45 Quick-fire poster presentations (one slide, 60 seconds)
13:45 – 15:15 COMPLEMENT TUTORIAL 2
3.1 Complement & therapeutics – Matthew Pickering
3.2 Complement & therapeutics – Claire Harris
4.1 Diagnostics; genetics – David Kavanagh
4.2 Diagnostics; biomarkers/assays –Loek Willems and Erik Toonen
15:45 – 17:05 ABSTRACT PRESENTATIONS
1550 – 1605 Lack of Complement Factor H contributes to endothelial cell injury in Shiga toxin Haemolytic Uraemic Syndrome, Emily Bowen
1605 – 1620 Safety, Tolerability and Pharmacodynamic Effects of ARO-C3, a Subcutaneously Administered Investigational RNAi Therapeutic Targeting Complement C3, in Adult Healthy Volunteers, Hamid Moradi
1620 – 1635 GWAS of plasma complement protein levels reveals functional effects of Alzheimer’s disease risk loci, Aurora Veteleanu
1635 – 1650 Complement receptor 1 is expressed on brain cells and impacts roles of microglia relevant to Alzheimer’s disease, Nikoleta Daskoulidou
1650 – 1705 Complement inhibitors for age-related macular degeneration (AMD): A Cochrane systematic review and meta-analysis, Nikolaos Tzoumas
17:05 – 18:05 Guest lecture "Cancer and Inflammation", Professor Sir Leszek Borysiewicz
18:15 – Poster presentations and Drinks Reception
19:30 – Conference Dinner
Sponsor of Conference Dinner
Tuesday, April 4th: SYMPOSIUM
08:45 – 12:15 SESSION 1: THERAPIES
08:45 – 09:15 Therapeutic targets – overview - Claire Harris
09:15 – 09:45 Anti-complement drugs in disease; Lessons from animal models – Kevin Marchbank
09:45 – 10:15 C5 vs. C3 based therapeutic approaches in kidney disease (including eculizumab withdrawal trials - Neil Sheerin
10:15 – 10:45 C5 vs. C3 based approaches in PNH - Richard Kelly
11:15– 11:45 Targeting complement at the genetic level - Scott Ellis
11:45 – 12:15 Designing anti-complement drugs through structural studies - Jean Van Den Elsen & Alex Macpherson
13:30 – 15:30 SESSION 2: Mechanisms and Diagnostics
13:30 – 14:00 Complement and genetics - Santiago Rodriguez de Cordoba
14:00 – 14:30 Pitfalls in complement analyses – Erik Toonen
14:30 – 15:00 New technologies for studying complement in brain – Soyon Hong
15:00 – 15:30 Lectin Pathway - Wilhelm Schwaeble
15:30 – 15:45 Prizes for best posters / presentations / tutor
15:45 – 16:30 Round table discussion
Is there a single best target for anti-complement drugs?
FULL PROGRAMME
POSTER PRESENTATIONS
POSTER DIMENTIONS
Posters should be in A0 (841 mm x 1189 mm), in portrait orientation.
LIST OF SUBMITTED POSTERS
Sponsor of Prizes for best poster and oral presentations
Event Location
Cardiff University
Hadyn Ellis Building
Maindy Road,
CF24 4HQ Cardiff
Dinner on April 3rd
Cardiff University
Aberdare Hall
Corbett Road,
CF10 3UP Cardiff
Become a Sponsor
A number of sponsor opportunities are available for companies looking to meet new customers and reinforce
existing relationships.
Posters, refreshments, coffee, and all networking breaks will take place in the exhibit hall to ensure high-quality networking.
Contact us for more details on our sponsorship opportunities
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